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European Network of Centres for Pharmacoepidemiology and Pharmacovigilance
News article3 July 2013European Medicines Agency1 min read

Second revision of the ENCePP Guide on Methodological Standards in Pharmacoepidemiology

The Guide continues to be the single most downloaded document on the ENCePP website with over 30,000 hits in 2012. The Guide is updated annually to maintain its dynamic nature and ENCePP has just published a second revision. New sections on ‘Effect modification’ and ‘Handling of missing data’ are included. A set of ‘Specific topics’ with two chapters on ‘comparative effectiveness research’ and ‘vaccine safety and effectiveness’ has also been inaugurated.

The revised guide continues to offer a single overview document and web resource for methodological guidance for both experienced and new researchers in pharmacoepidemiology and pharmacovigilance. For each topic covered, direct electronic access is given to internationally agreed recommendations and key points from important guidelines, published articles and textbooks after an introductory review. Where relevant, gaps in guidance have been addressed with what ENCePP considers good practice. 

For ease of access to individual topics of interest, a web version has been published with links to each chapter and section. A consolidated version is also available for download.

Related information:

» ENCePP Guide on Methodological Standards in Pharmacoepidemiology


Publication date
3 July 2013
European Medicines Agency